A compounded weekly injection that pairs semaglutide — the clinically proven GLP-1 — with vitamin B12, commonly included to support energy and help ease nausea. Prescribed online, shipped from U.S. pharmacies.
Semaglutide + B12 is a compounded weekly injection that combines semaglutide — a GLP-1 receptor agonist used for medically-supervised weight loss — with vitamin B12. The B12 is commonly added to support energy and to help some patients tolerate GLP-1-related nausea. Because it combines ingredients, this formulation is prepared by a 503A compounding pharmacy.
Built on semaglutide, one of the most rigorously studied GLP-1 medications.
Vitamin B12 is commonly included to support energy and help ease nausea.
A single weekly injection fits into real life — no daily routine to keep up with.
Prepared for the individual patient by a 503A partner pharmacy under a valid prescription.
The GLP-1 component mimics a natural gut hormone that signals fullness to your brain and helps regulate appetite.
It slows stomach emptying and acts on appetite centers, so you feel satisfied sooner and blood sugar stays steadier.
Vitamin B12 is commonly added to support energy and to help some patients with GLP-1-related nausea during titration.
Semaglutide + B12 may be a fit for adults pursuing medically-supervised weight loss who want the proven weekly GLP-1 and may benefit from added B12 for energy or nausea support during titration.
It is not appropriate for everyone. A licensed provider reviews your health history to decide whether this compounded formulation — or another option — is right for you.
Start your visit →Answer a few questions online about your health, goals, and history. No appointment needed.
A licensed provider reviews your information and, if appropriate, writes a prescription.
If prescribed, your compounded medication ships discreetly from a 503A U.S. pharmacy.
This is a compounded formulation; your provider selects the right starting dose and titration schedule.
Semaglutide + B12 is not for those with a personal or family history of medullary thyroid cancer (MTC) or MEN2, or a history of pancreatitis. Tell your provider about your full medical history, allergies (including to B12/cobalamin), and every medication you take.
Seek immediate care for severe or persistent abdominal pain (possible pancreatitis) or signs of an allergic reaction.
This page was written and is periodically reviewed for medical accuracy in line with clinical guidance followed by the independent, licensed medical providers in the ForbiddenRx network. Last reviewed: July 2026.
This page is educational and is not medical advice.
Complete a quick online visit. A licensed provider reviews your information and, if appropriate, your semaglutide + B12 ships to your door.
Start your visit →